Rapid intestinal and serum metabolism via esterase-mediated hydrolysis to a thiolactone , which is then converted, via CYP450-mediated oxidation, to an active metabolite (ja)
Rapid intestinal and serum metabolism via esterase-mediated hydrolysis to a thiolactone , which is then converted, via CYP450-mediated oxidation, to an active metabolite (ja)